Physiological leucocytosis

Extreme leucocytosis: not always leukaemia.

Three patients were analysed for an extreme leucocytosis (>50x10(9)/l) because leukaemia was suspected. In all three patients the leucocytosis proved to be caused by a leukaemoid reaction. This reaction was associated with a hepatic angiosarcoma in the first patient, with a Salmonella infection in the second patient and with a necrotic leg abscess in the third patient. Retrospectively, 25 patie...

Marked Leucocytosis Masquerading Chronic Leukemia: case series

The term leukemoid reaction (LR) was initially coined by Krumbhaar in 1926. Since then, a lot of studies have been conducted to understand the pathophysiology and its role in various diseases. The cut off value for LR has not yet been defined;however a clear cut distinction has to be made between LR and chronic leukemia as both are treated differently. Present study is a case series of ten pati...

Extreme leucocytosis and splenomegaly in metastasised melanoma.

A 63-year-old woman presented to the internist with fatigue, cough, low-grade fever, splenomegaly and leucocytosis up to 130 x 10(9)/l. Although a diagnosis of chronic myelogenous leukaemia was initially entertained, she turned out to have a metastasised melanoma. The differential diagnosis and workup is discussed, as well as potential mechanisms by which the tumour could have induced the leuco...

The Leucocytosis of Labor and the Puerperium

The first investigators to find a leucocytosis in pregnancy were)/[oteschott and l~asse (1). This observation has been confirmed by It has been found that most primiparee have a leucocytosis in the later months of pregnancy, the average connt being about 13,000. About 5 per cent of multiparm have a leucocytosis, usually less high than the primiparm. Virchow suggests as an explanation of the ]eu...

Leucocytosis in Pelvic Disease in the Female